In a year full of major advances, over-hyped findings and controversial studies, it was tough for the Wired Science staff to choose which breakthroughs were the biggest in 2010. So we've collected the ones that stood out the most to us.

From synthetic life and three-parent embryos to the possibility of a new human ancestor and a habitable exoplanet, here are the breakthroughs that made us shout "Science!" the loudest this year.